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methionine- and choline-sufficient (mcs) diet cat# a02082003b  (research diets inc)

 
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    research diets inc methionine- and choline-sufficient (mcs) diet cat# a02082003b
    Methionine And Choline Sufficient (Mcs) Diet Cat# A02082003b, supplied by research diets inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Ponatinib reduced the liver fibrosis and injury induced <t>by</t> <t>MCD.</t> (A) The relative mRNA levels of genes associated to fibrosis were tested by qPCR. (B) Hepatic gene expression associated with inflammation was measured by qPCR in mice fed with <t>MCS</t> or MCD diet and treated with ponatinib or vehicle for 4 weeks. (C, D) The levels of liver function markers AST (C) and ALT (D) in the serum of mice. n = 5, Data represent mean ± SEM. * P < 0.05, *** P < 0.001 vs. MSD group. # P < 0.05, ## P < 0.01, ### P < 0.001vs. MCD group.
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    Ponatinib reduced the liver fibrosis and injury induced <t>by</t> <t>MCD.</t> (A) The relative mRNA levels of genes associated to fibrosis were tested by qPCR. (B) Hepatic gene expression associated with inflammation was measured by qPCR in mice fed with <t>MCS</t> or MCD diet and treated with ponatinib or vehicle for 4 weeks. (C, D) The levels of liver function markers AST (C) and ALT (D) in the serum of mice. n = 5, Data represent mean ± SEM. * P < 0.05, *** P < 0.001 vs. MSD group. # P < 0.05, ## P < 0.01, ### P < 0.001vs. MCD group.
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    Ponatinib reduced the liver fibrosis and injury induced <t>by</t> <t>MCD.</t> (A) The relative mRNA levels of genes associated to fibrosis were tested by qPCR. (B) Hepatic gene expression associated with inflammation was measured by qPCR in mice fed with <t>MCS</t> or MCD diet and treated with ponatinib or vehicle for 4 weeks. (C, D) The levels of liver function markers AST (C) and ALT (D) in the serum of mice. n = 5, Data represent mean ± SEM. * P < 0.05, *** P < 0.001 vs. MSD group. # P < 0.05, ## P < 0.01, ### P < 0.001vs. MCD group.
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    Ponatinib reduced the liver fibrosis and injury induced <t>by</t> <t>MCD.</t> (A) The relative mRNA levels of genes associated to fibrosis were tested by qPCR. (B) Hepatic gene expression associated with inflammation was measured by qPCR in mice fed with <t>MCS</t> or MCD diet and treated with ponatinib or vehicle for 4 weeks. (C, D) The levels of liver function markers AST (C) and ALT (D) in the serum of mice. n = 5, Data represent mean ± SEM. * P < 0.05, *** P < 0.001 vs. MSD group. # P < 0.05, ## P < 0.01, ### P < 0.001vs. MCD group.
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    Ponatinib reduced the liver fibrosis and injury induced by MCD. (A) The relative mRNA levels of genes associated to fibrosis were tested by qPCR. (B) Hepatic gene expression associated with inflammation was measured by qPCR in mice fed with MCS or MCD diet and treated with ponatinib or vehicle for 4 weeks. (C, D) The levels of liver function markers AST (C) and ALT (D) in the serum of mice. n = 5, Data represent mean ± SEM. * P < 0.05, *** P < 0.001 vs. MSD group. # P < 0.05, ## P < 0.01, ### P < 0.001vs. MCD group.

    Journal: Frontiers in Pharmacology

    Article Title: Ponatinib alleviates non-alcoholic steatohepatitis through TFEB-mediated autophagy

    doi: 10.3389/fphar.2024.1505768

    Figure Lengend Snippet: Ponatinib reduced the liver fibrosis and injury induced by MCD. (A) The relative mRNA levels of genes associated to fibrosis were tested by qPCR. (B) Hepatic gene expression associated with inflammation was measured by qPCR in mice fed with MCS or MCD diet and treated with ponatinib or vehicle for 4 weeks. (C, D) The levels of liver function markers AST (C) and ALT (D) in the serum of mice. n = 5, Data represent mean ± SEM. * P < 0.05, *** P < 0.001 vs. MSD group. # P < 0.05, ## P < 0.01, ### P < 0.001vs. MCD group.

    Article Snippet: The MCD diet and methionine and choline sufficient (MCS) diet were purchased from Research Diets Inc (Bergenfield, NJ, United States).

    Techniques: Gene Expression